THE 8 BREAKTHROUGH INNOVATIONS RESHAPING MEDICAL AESTHETICS

New Innovation Insider Section

Discover our new Innovation Insider Section by Benoît Chardon & Julien Vervel. Innovation is entering a new era defined by biological intelligence rather than cosmetic correction. Across skin, hair, body procedures, femtech and Al-driven technologies, the future of healthcare is regenerative, functional and deeply personalized, reshaping both clinical outcomes and the patient journey. Drawing on his experience in breakthrough innovation, Benoît Chardon explores how science, technology and biology converge to restore tissue, optimize function and anticipate care. In parallel, Julien Vervel challenges traditional B2B digital communication models in healthcare, redefining digital not as a tool, but as a growth ecosystem, designed to create value, meaning and sustainable performance for healthcare professionals

Benoît Chardon

Benoît Chardon is a global leader in medical aesthetics with a rare dual track record: category creating innovation and large-scale value creation.

Corporate Value Creation

Filorga – Created the brand and led skincare development; later acquired by Colgate-Palmolive for $1.4bn

CoolSculpting – Led international marketing; category-defining body contouring platform acquired by Allergan for $2.5bn

Allurion – Scaled revenue as CCO from $3m to $65m, leading to a $0.5bn NYSE IPO

Fastox – Board Member; contributed to acquisition by AbbVie

Innovation That Changed the Market

Restylane Skinboosters (15 years ago): shifted injectables from volume to skin quality, creating an entirely new treatment category Sculptra Relaunch (10 years ago): repositioned biostimulation as a long-term regenerative strategy, redefining collagen-based aesthetics.

Most recently, Benoît has been appointed to the IMCAS Industry Innovation Jury, as the main award of the IMCAS Innovation Tank and as Chairman of the AMWC Catalyst, reinforcing his position as a leading authority on disruptive innovation in medical aesthetics.

Julien Vervel

Julien Vervel is a digital expert specializing in the healthcare sector, with recognized expertise in structuring online visibility, managing medical branding, and adapting digital strategies to the ethical and regulatory requirements of the industry.

Digital Health Expertise

Managing Director of HEALTHCIE An agency specializing in SEO and digital strategies for professionals in medicine and aesthetic surgery.

Innovation Ecosystem

Recipient of French Tech Prépa 2020 Recipient of French Tech Incubation 2021 Selected for the 2021 Digital Talents Directory (Diversidays)

Institutional Engagements

Speaker at the French National Academy of Surgery on topics related to e-reputation and medical communication.

Speaker at leading congresses in surgery and aesthetic medicine: SFME, Prague Lab, AIME

Pharmaceutical Industry

Consulting Digital consultant for major players in the pharmaceutical and medical device industries: AbbVie, Pfizer, Vivacy, Global D

SKIN REGENERATION: WHERE BIOLOGY REPLACES VOLUME

AEROLASE - DUAL-WAVELENGTH IN & OUT SKIN RENEWAL (NEO ELITE + ERA ELITE)

Why It Matters: Reverse by Aerolase® delivers dermal remodeling and epidermal renewal in a single visit by combining Neo Elite (1064 nm Nd:YAG, 650-microsecond) for deep collagen stimulation with Era Elite (2940 nm Er:YAG, 300-microsecond) for controlled rejuvenation, helping physicians address texture, tone, laxity, and overall skin quality.

Clinical Impact: Treats surface texture and deeper dermal quality together, not as separate appointments, with consistent safety across all Fitzpatrick skin types (I–VI) Efficient for patients with busy schedules, with minimal, transient recovery reported in clinical use. All without requiring anesthetic.

Evidence: In a clinical evaluation of 25 women (ages 38–61) receiving a combined Neo Elite and Era Elite treatment in same treatment visit, punch biopsies (n=7) taken before and one month after treatment showed statistically significant increases in collagen type I (57%) and collagen type III (86%).

RoC – ULTIMATE ANTI-AGING SKINCARE ROUTINE

Why It Matters: RoC stands out through pharmaceutical-grade clinical proof in skincare with the first clinical study performed with 35 clinics on a 5-step skincare at home routine enabling 200 patients to achieve 9,6 years skin rejuvenation in 3 months.

Clinical Impact:

• Bridges medical aesthetics and daily skin longevity
• Ideal formulations enabling the potent combination of Retinol, Vitamin C and Hyaluronic Acid with high tolerability on all skin types

Evidence: ROC35 Study on 200 patients, 35 clinics, real-world conditions over 90 days. Demonstrated 9,6 skin rejuvenation and significant improvements in wrinkles, firmness, radiance, and overall skin quality— positioning RoC among the most clinically validated anti-aging brands globally.

TIENCE – REGENERATIVE BIOREMODELING

Why It Matters: Tience® is the only cell-free injectable derived from human adipose bioactives, activating intrinsic skin repair without fillers, fat transfer nor foreign particles. Unlike HA fillers (volume), fat grafting (invasive, variable) or bio stimulants (inflammatory particles), it targets collagen, elastin, HA natural synthesis, and microcirculation.

Clinical Impact:

• Reduces need for invasive fat grafting when skin quality is the goal
• Ready to use human origin regenerative aesthetics

Evidence: 1,000+ treatments with no serious adverse events; documented safety study (39 subjects). Independent data shows ~21% wrinkle reduction in periorbital skin at 4 months.

HAIR REGENERATION: MOLECULAR PRECISION OVER SYSTEMIC THERAPY

DERMA GENE – DNAZYME THERAPY

Why It Matters: First-in-class topical DNAzyme targeting 5a-reductase (types 1 & 2) and androgen receptor mRNA, suppressing DHT signaling locally— without systemic exposure.

Clinical Impact :

• Ready-to-use nano fat initially developed for therapeutic indications (scars, acne & hair growth) with clinical trials on the first 2
• Also demonstrated transformative results on skin quality and under eye

Evidence: Preclinical models demonstrate significant downregulation of 5a-reductase (types 1 & 2) and androgen receptor expression at the follicular level. Early clinical studies show meaningful reductions in hair shedding and stabilization of hair density within 12–16 weeks, with no detectable changes in systemic hormone levels—supporting a favorable safety profile versus oral anti-androgen therapies.

FAT REMODELING: FROM ARTISAN PROCEDURES TO ROBOTIC PRECISION

SYNTR HEALTH – FAT PROCESSING REINVENTED

Why It Matters: FDA-cleared robotic purification and microsizing of fat, preserving regenerative cells and standardizing outcomes.

Clinical Impact:

• Reduces procedure time
• Improves graft consistency and survival

Evidence: Published multi-center adoption report higher cell yield, improved graft handling, and durable volumetric outcomes compared with manual fat processing, with high surgeon satisfaction. 82% of patients achieved “very satisfied” or “somewhat satisfied” FACE-Q satisfaction scores for mid-face and nasolabial volume correction.

FEMTECH: MINIMALLY INVASIVE, WOMEN-FIRST AESTHETICS

MIA FEMTECH – TISSUE PRESERVATION BREAST ENHANCEMENT

Why It Matters: A tissue-preserving, minimally invasive alternative to traditional implants, focused on natural breast enhancement without scar on the breast and without general anesthesia.

Clinical Impact

• Outpatient, low-trauma procedures
• Expands access to breast aesthetics to women looking for less down time and most natural results

Evidence: Now supported by 5-year clinical follow up data showing >90% patient satisfaction, stable aesthetic outcomes over time, and a very low complication rate (<2%), with no implant-related long-term safety concerns—confirming durability, safety, and high acceptance of this minimally invasive approach.

DIGITAL ENABLEMENT: WHEN AI BECOMES CLINICAL INFRASTRUCTURE

ADOREAL – AI-POWERED PATIENT JOURNEY PLATFORM

Why It Matters: Adoreal digitizes and optimizes the aesthetic patient journey, addressing a critical gap between clinical excellence and patient conversion, engagement, and retention.

By structuring consultations, treatment education, visualization, and follow-up through AI-driven workflows, Adoreal improves clarity, trust, and decision-making while reducing physician time per consultation.

Target Users: Aesthetic clinics and physician-led practices seeking higher treatment acceptance, consistency, and patient lifetime value.

Evidence: Users show improved consultation efficiency, higher conversion rates, and stronger patient satisfaction—positioning Adoreal as a foundational technology layer for modern aesthetic practices.

THE APPLICATION BRINGING DATA BACK TO THE HEART OF SEO STRATEGIES

MY HEALTHCIE – A GAME CHANGER FOR MANAGING YOUR SEO STRATEGIES

Why It Matters: MY HEALTHCIE recenters data at the heart of SEO, SEA, and GEO strategies in aesthetic medicine, transforming fragmented visibility metrics into clear, actionable insights. The platform helps link digital performance to patient acquisition, brand awareness, and ROI.

Target Users: Aesthetic clinics, physician-led practices, healthcare groups, and industry brands seeking better control of their digital visibility.

Evidence: Users benefit from clearer performance tracking, improved decision-making, and measurable impact of digital actions—positioning MY HEALTHCIE as a strategic monitoring layer for the sector.