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Dr. Monika Kavková
Aesthetic medicine

REJUVENATION OF THE LIPS AND PERIORAL REGION IN MATURE WOMEN

By Dr. Monika Kavková

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"Rejuvenating the lips and perioral region in mature women demands a conservative, anatomyguided, and psychologically sensitive approach."

Abstract

Background: Lips are central to facial beauty and one of the earliest features to show age-related changes. Mature patients increasingly seek perioral rejuvenation that appears natural rather than transformative. Objective: To review age-related changes of the lips, psychological considerations in older patients, and outline a structured, anatomy-based approach for safe and harmonious treatment. Methods: This review synthesizes current literature and practical injection techniques, emphasizing layered correction, deep support restoration, and integration of minimally invasive tools.

Conclusion: Treating aging lips requires more than simple augmentation. Addressing structural support, correcting perioral lines, and integrating full-face balance are key to achieving subtle, age-appropriate, and lasting outcomes.

Keywords

Lip rejuvenation, perioral region, aging, hyaluronic acid, fillers, neuromodulators, anatomy-guided technique, facial harmony

Introduction

The lips and surrounding perioral structures are essential to facial expression, aesthetics, and identity. In women, they are closely associated with attractiveness, youth, and femininity. However, the lips are also among the first areas to show signs of aging. Older patients often express reluctance toward dramatic changes; they fear overfilling, distortion of natural features, and visible evidence of cosmetic intervention. They seek refinement rather than transformation — a fresher, softer, and authentic appearance.

To meet these expectations, clinicians must understand not only the anatomy and age-related changes of the lips, but also the psychological profile of mature patients and the principles of safe, layered rejuvenation.

Anatomical and Functional Changes of the Aging Lip

Soft Tissue and Skin Changes

  • Loss of volume, shape, and definition.
  • Flattening of the vermilion border and fading of the Cupid’s bow.
  • Thinning of the red lip and elongation of the upper lip.

Orbicularis Oris Muscle (OOM) Changes

With age, the orbicularis oris muscle becomes thinner and weaker, while surrounding connective tissue thickens. This imbalance between skin and muscle aging leads to vertical perioral rhytids, lip retrusion, and loss of structural support.

Skeletal Changes

Maxillary and mandibular bone resorption reduces the bony foundation, accelerating soft tissue collapse.

Patient Psychology and Expectations

Older patients rarely want «new lips.» They want familiar lips that look younger. They fear excessive lip volume, disproportionate results, and being visibly recognized as treated. They value subtle improvement, restored definition, and natural integration with the rest of the face. Therefore, consultation and expectation management are critical.

Principles of Lip and Perioral Rejuvenation in Mature Women

  • Treat the face, not just the lips.
  • Correct deep support first.
  • Rebuild shape and definition before volume.
  • Address perioral lines conservatively.
  • Integrate neuromodulation when indicated

Stepwise Technical Protocol

  • Localize labial arteries.
  • Release adhesions using blunt cannula subcision.
  • Create a deep foundation layer beneath the OOM.
  • Restore vermilion and lip body with controlled HA filler injections.
  • Refine corners and wrinkles with soft filler in microboluses.
  • Support adjacent areas such as cheeks, NLF, marionette lines.
  • Add neuromodulators when indicated.

Clinical Pearls

  • Less is more — avoid excessive volume.
  • Treat in layers — from deep skeletal support to superficial skin.
  • Combine HA fillers, neuromodulators, and biostimulation.
  • Educate patients and explain realistic outcomes.
  • Avoid isolated corrections — lips must match facial context.

Conclusion

Rejuvenating the lips and perioral region in mature women demands a conservative, anatomyguided, and psychologically sensitive approach. By rebuilding deep support, restoring natural definition, and refining surface wrinkles in a layered manner, clinicians can achieve subtle, harmonious, and long-lasting results. Modern techniques using HA fillers, neuromodulators, and full-face planning respect both facial proportions and the patient’s desire to look refreshed, not transformed.

References

  • Swift A, Liew S, Weinkle S, Garcia JK, Silberberg MB. The Facial Aging Process From the “Inside Out.” Aesthetic Surg J. 2020 Dec 16.
  • Shaw RB Jr, Kahn DM. Aging of the midface bony elements: a three dimensional computed tomographic study. Plast Reconstr Surg. 2007.
  • Hiratsuka Dalmedo V. Lips and the perioral area: anatomical considerations for safer and natural results. PMFA Journal, Aug 2023.
  • Cotofana S, Pearce T. Practical anatomy for perioral injection techniques. 2022.

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